227Th-EDTMP: A potential therapeutic agent for bone metastasis
نویسندگان
چکیده
منابع مشابه
227Th-EDTMP: a potential therapeutic agent for bone metastasis.
The biodistribution of 227Th-EDTMP and retention of its daughter nuclide 223Ra were examined. 227Th-EDTMP was found to show high uptake and long-term retention in bone. The clearance of 227Th-EDTMP from blood and soft tissues was rapid and the femur-to-tissue uptake ratios reached more than 100 within 30 min for all tissues except the kidney. Seven and 14 days after injection of 227Th-EDTMP, th...
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متن کاملTreatment efficacy of 153Sm-EDTMP for painful bone metastasis
INTRODUCTION Involvement of the skeleton can cause an excruciating pain in two-thirds of terminal patients with a history of malignancy. Due to several limitations of other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have an important role in palliation of pain from bone metastases. Although the...
متن کاملtreatment efficacy of 153sm-edtmp for painful bone metastasis
introduction: involvement of the skeleton can cause an excruciating pain in two-thirds of terminal patients with a history of malignancy. due to several limitations of other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have an important role in palliation of pain from bone metastases. although th...
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ژورنال
عنوان ژورنال: Nuclear Medicine and Biology
سال: 2004
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2004.05.001